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Machine learning based combination of multi-omics data for subgroup identification in non-small cell lung cancer
Non-small Cell Lung Cancer (NSCLC) is a heterogeneous disease with a poor prognosis. Identifying novel subtypes in cancer can help …
Seema Khadirnaikar, Sudhanshu Shukla, S R Mahadeva Prasanna
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An epithelial-mesenchymal plasticity signature identifies two novel LncRNAs with the opposite regulation
The epithelial to mesenchymal transition (EMT) is crucial for cancer progression and chemoresistance. EMT is a dynamic process with …
Pranjal Kumar, Seema Khadirnaikar, Nikita Bhandari, Annesha Chatterjee, Sudhanshu Shukla
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Development and validation of stemness associated LncRNA based prognostic model for lung adenocarcinoma patients

BACKGROUND: An increasing number of studies are indicating that the stemness phenotype is a critical determinant of the Lung …

Annesha Chatterjee, Seema Khadirnaikar, Sudhanshu Shukla
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Genetic and epigenetic landscape of leukocyte infiltration identifies an immune prognosticator in lung adenocarcinoma

BACKGROUND: Leukocyte infiltration plays an critical role in outcome of various diseases including Lung adenocarcinoma (LUAD). …

Seema Khadirnaikar, Annesha Chatterjee, Sudhanshu Shukla
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Identification and Characterization of Senescence Phenotype in Lung Adenocarcinoma with High Drug Sensitivity
Lung adenocarcinoma (LUAD) is a major health problem and has poor prognosis. Heterogeneity is a central determinant of the treatment …
Seema Khadirnaikar, Annesha Chatterjee, Sudhanshu Shukla
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A greedy algorithm-based stem cell LncRNA signature identifies a novel subgroup of lung adenocarcinoma patients with poor prognosis
Cancer stem cells play an essential role in therapy response and aggressiveness of various cancers, including lung adenocarcinoma …
Seema Khadirnaikar, Annesha Chatterjee, Pranjal Kumar, Sudhanshu Shukla
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PILAR1, a novel prognostic LncRNA, reveals the presence of a unique subtype of lung adenocarcinoma patients with KEAP1 mutations
Lung Adenocarcinoma (LUAD) is the most common cause of lung cancer-related deaths. Long non-coding RNAs (LncRNAs) play an essential …
Pranjal Kumar, Seema Khadirnaikar, Sudhanshu Shukla
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Development and validation of an immune prognostic signature for ovarian carcinoma

Background: Ovarian cancer (OC) causes a significant proportion of cancer-related deaths in women. Recently, immunotherapy has emerged …

Seema Khadirnaikar, Pranjal Kumar, Sudhanshu Shukla
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A novel LncRNA-based prognostic score reveals TP53-dependent subtype of lung adenocarcinoma with poor survival
The prognostic signatures play an essential role in the era of personalised therapy for cancer patients including lung adenocarcinoma …
Pranjal Kumar, Seema Khadirnaikar, Sudhanshu Shukla
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Mobile monitoring of air pollution using low cost sensors to visualize spatio-temporal variation of pollutants at urban hotspots
This paper deals with the development of a smart personal air quality monitoring system (SPAMS) for real time air quality monitoring. …
Shiva Nagendra S M, Pavan Reddy Yasa, M V Narayana, Seema Khadirnaikar, Pooja Rani
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